DXA is an accurate, cost-effective imaging method with a minimal radiation dose, enabling clinical trials to enroll a large number of patients and perform multiple follow-up examinations in a short time frame, thereby collecting a vast amount of data to understand the drug’s mechanism of action and provide key evidence of its safety and efficacy in relation to bone health.
Despite its many advantages, DXA is also very limited, as it only provides a two-dimensional assessment of bone mineral density, which limits a complete understanding of bone health due to the lack of key data on the condition and response of the cortical and trabecular bone compartments. Quantitative computed tomography (QCT), an alternative, can help answer these otherwise unexplored questions. However, QCT also has its limitations. QCT is an expensive imaging method with a high radiation dose, which consequently increases the cost of the clinical trial, makes its approval more difficult, and limits the number of patients and data points that can be obtained.
What if you could obtain quantitative computed tomography (QCT-like) data from a routine DXA scan? Well, now it’s possible with 3D-Shaper® as a Service (SaaS), an innovative software solution that bridges the gap between DXA-based and QCT-based assessments by providing patient-specific, QCT-like three-dimensional analysis from a standard two-dimensional DXA image. This means more patients, more time points, and easier IRB approvals – all for a fraction of the cost.
Explore up to 71 bone parameters with in-depth three-dimensional image analysis
Display average change with detailed three-dimensional visualizations
Bone strength simulation with the latest innovation – Finite Element Analysis (FEA) from DXA
